The study will be presented at the annual meeting of the American Society for Radiation Oncology (ASTRO).

“Our study evaluated the skin toxicity and early cardiac toxicity of concurrent Trastuzumab and radiation therapy treatment in the adjuvant setting,” says Penny Anderson, M. D. , radiation oncologist at Fox Chase and lead author on the study. “We found that there was an extremely low rate of acute radiation dermatitis and cardiac toxicity in patients who received this type of treatment. ”

The study followed 85 breast cancer patients who received adjuvant Trastuzumab while also receiving a course of adjuvant radiation therapy, as well as 85 breast cancer patients who only received adjuvant radiation therapy. Acute dermatitis was grade 2 in 15% and grade 3 in 2% of the patients receiving concurrent treatment, likewise grade 2 and grade 3 dermatitis was observed in 14% and 2 % of patients only receiving radiation therapy–there was only one patient who developed a grade > 2. There were no differences in cardiac toxicity between the two groups.

“The results of this study show that it is safe to use both Trastuzumab and radiation therapy in an adjuvant setting, when clinically indicated,” adds Anderson. “We would like to see longer follow-up to evaluate the potential differences in late cardiac toxicity. ”

Terramed Alliance is a non-profit charity organization dedicated to research, education and advocacy of breast cancer. One of the vision of Terramed Alliance is to provide this community and Internet users with a charity based research and education entity. Advocacy of breast cancer through education is vital to the reduction of this disease.

Some research has indicated that PABC has a worse outcome than other breast cancers; however, this could also be attributable to young age, since most women with PABC tend to be young and breast cancer in young women tends to have a worse prognosis.

Researchers from M. D. Anderson Cancer Center analyzed data from 652 women ages 35 and younger who were diagnosed with breast cancer between 1973 and 2006. The group included 104 women with PABC—51 who were diagnosed during their pregnancy and 53 who were diagnosed within the following year.

The researchers observed that the tumors in the pregnant women were more advanced upon diagnosis; however, this could be because the pregnancy masked symptoms, leading to a delayed diagnosis. The data indicated that the rates of overall survival, distant metastases, and locoregional recurrence were similar among women with PABC and those with non-PABC.

The researchers concluded that pregnancy in and of itself does not predict for worse outcomes in women with breast cancer; however, they stressed the importance of early diagnosis and treatment. This is a complex issue due to the perceived notion of endangering the fetus during treatment. Research will likely be ongoing to evaluate this issue.

Terramed Alliance is a non-profit charity organization dedicated to research, education and advocacy of breast cancer. One of the vision of Terramed Alliance is to provide this community and Internet users with a charity based research and education entity. Advocacy of breast cancer through education is vital to the reduction of this disease.

Researchers from the University of Texas M. D. Anderson Cancer Center in Houston sought to determine which form of breast cancer treatment – breast-conserving therapy, mastectomy alone or mastectomy with adjuvant radiation – better benefits younger women with either Stage I or Stage II breast cancer.

A total of 652 young women with breast cancer from 1973 to 2006 were studied, with 197 of the patients having received breast-conserving therapy, 237 having received a mastectomy and 234 having received mastectomy with adjuvant radiation. The study authors confirmed that younger breast cancer patients do have relatively high locoregional recurrence rates, but that patients with Stage II disease achieved the best locoregional control rates with mastectomy plus adjuvant radiation therapy. Patients with Stage I disease had similar outcomes with breast-conserving therapy and mastectomy, but adding chemotherapy to either treatment was beneficial.

“Locoregional recurrence after optimal breast cancer treatment in young women remains a significant problem,” Beth Beadle, M. D. , Ph. D. , a resident at M. D. Anderson and lead author of the study, said. “Our study hopefully will help radiation oncologists plan therapies for younger breast cancer patients, who have inferior outcomes compared to older patients, and generate new interest in prospective studies to evaluate the best treatment strategies for these young women. ” American Society for Therapeutic Radiology and Oncology (2009). Younger Breast Cancer Patients Have Greater Chance Of Recurrence, Especially After Certain Treatments. ScienceDaily.

Terramed Alliance is a non-profit charity organization dedicated to research, education and advocacy of breast cancer. One of the vision of Terramed Alliance is to provide this community and Internet users with a charity based research and education entity. Advocacy of breast cancer through education is vital to the reduction of this disease.   For any requests and enquiries, please contact at us: cancer@terramedalliance. us www. terramedalliance. us

The hypertension leads to the modifiable risk factor that leads to the coronary heart disease, stroke, congestive heart failure, end stage renal disease, and peripheral vascular disease that lead to causes for death. In most cases, hypertension is easily detected and usually controllable with lifestyle modifications—such as diet and exercise—and medication. Therefore, health care professionals must not only identify and treat patients with hypertension but also promote a healthy lifestyle and preventive strategies to decrease the prevalence of hypertension in the general population.

Hypertension, or high blood pressure, is often referred to as a “silent killer” because there are usually no signs or symptoms. It occurs when the pressure of the blood flowing through your arteries is too high. This increased pressure puts extra stress on vital organs such as the heart, the kidneys, and the blood vessels. This can lead to more serious consequences if it is not treated. It is similar to what happens when water is run through pipes at too high a pressure. Something eventually gives.

The information provided is like supplement information just a medical advice. Your doctor with whom you get the treatment is your main source of information about your condition and how to manage your suffer.
The normal blood pressure is below 120/80; blood pressure between 120/80 and 139/89 is called “pre-hypertension”, and a blood pressure of 140/90 or above is considered high blood pressure. This blood pressure increases the risk of suffering from some of the heart disease, kidney disease, hardening of the arteries, eye damage and brain damage. When this occurs it leads to the result of the long duration of the high blood pressure.

To normalize the blood pressure it is important that there should the regular diagnosis of it and thereby it can be prevented with the complications. This is a major public health problem in the world as it found one among the four adults. This affects the elderly citizens who are more than 50 years of age and if they are affected then represents the greater risk if they are not treated at the early stage.
If you want to have no need to worry then you should have the check of your blood pressure and pulse reading regularly. Have to frequently visit the physician for the check or if you feel like any of the symptoms like the low number of BP, the higher number of BP or if there is irregular pulse rate.

Take the following steps to try to prevent hypertension:

• Losing weight is very important step to take with non-drug treatment that prevents the hypertension.
• Try eating low-fat, high fiber diet that is rich in fruits and vegetables. Salt must be used in moderation but no more than 2300mg per day. Unless otherwise directed by your physician.
• Aerobic exercising is a very important step. It will help lower blood pressure and prevent hypertension.
• Quit smoking. Hypertension and smoking significantly increases your risk of experiencing a stroke.
• Try reducing the stress in your life. When you experience stress in your life, your arteries and veins constrict, which is damaging to your health.
• Knowing your family’s health history is important. If a close relative lives with hypertension you are more likely to suffer from this disease. Be more careful in checking your blood pressure.
• High blood cholesterol can narrow arteries and make you more prone to hypertension. Have a physician check your cholesterol once a year.
• Keep a journal of your cholesterol, blood pressure and pulse. Take this along with you to your physician’s office. This will give him a more accurate view on your blood pressure and pulse rate.
• The ideal blood pressure should be 120/80. Keeping your blood pressure at 120/80 is your goal.

Though the disease has a cure but it is a require to better prevent than to suffer from.

Garlic

Although garlic is a spice, it has long been considered a superfood for its antioxidant qualities. Garlic is chock-o-block full of antioxidants which help to fight off free radical that damage and kill your body’s cells. It helps to prevent high cholesterol and high blood pressure, and it’s credited with improving your immune system. Garlic also helps to protect against cancer.

Spinach

Spinach, like all leafy green vegetables, is extremely rich in antioxidants. Spinach is also a great source of vitamin A, vitamin C, vitamin E, Vitamin K, Magnesium, potassium, folic acid, calcium, zinc, iron, protein, copper and vitamins B2 and B6. Well, if all that’s not enough to prove what a powerhouse superfood spinach is, nothing else will. To get the greatest benefit from spinach it should be steamed, boiled quickly, or eaten fresh.

Almonds

Almonds are also an amazing superfood everyone should eat. Almonds provide lots of nutrients including vitamin E, protein, good fats, amino acids and dietary fiber. The protein in almonds serves to counteract the negative effects of excessive amount of sodium in the body which can lead to blood pressure problems. Almonds are also rich in magnesium, potassium and phosphorus. The fiber in Almonds will make you feel fuller which will help with weight control.

Blueberries

Blueberries take the cake when it comes to antioxidants. These little rounds blue berries pack a punch of goodness with every handful. Not only are they one of the best sources of antioxidants, blueberries contain vitamin C, vitamin E, fiber and are a low caloric food. Blueberries help to prevent cancer, cardiovascular disease, and the fiber content in them helps you to feel fuller which may keep you out of the snack jar and help you to better manage your weight.

Omega3 fatty acids

Omega 3 fatty acids help your body to increase the good cholesterol (HDL), aids in anticoagulation of the blood (Prevents blood clotting) and are thought to lower high blood pressure. Foods rich in omega 3 fatty acids include salmon, tuna, mackerel, prawns and herring.

Tomatoes

Tomatoes are also an amazing superfood everyone should eat. Tomatoes are loaded with beta-carotene and vitamin E which help to prevent or treat low levels of vitamin A. Tomatoes are also extremely rich in lycopene which has antioxidant properties the help to protect your body from developing a variety of cancers.

Whole grains

Many people include whole grains in their diets as a means of controlling cravings and helping to control weight. Whole grains will also stimulate your stomachs good bacteria which will help to increase your body’s resistance to diseases. Whole grains also boost the body’s immune system which makes it stronger for fighting off infection and disease. Brown rice and whole grain breads are great sources of whole grains.

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Causes Pulmonary Hypertension:

Pulmonary hypertension results from constriction, or tightening, of the blood vessels that supply blood to the lungs. Consequently, it becomes difficult for blood to pass through the lungs, making it harder for the heart to pump blood forward. This stress on the heart leads to enlargement of the heart and eventually fluid can build up in the liver and tissues, such as the in the legs. Affected patients can sometimes notice increasing shortness of breath and dizziness.
What are the symptoms of Hypertension?
If you have hypertension, chances are that you may not have any symptoms at all. Hypertension is often called the “silent killer” because most people who have it do not feel sick, but if left uncontrolled, it can lead to a heart attack or kidney disease. This is why it is so important to treat hypertension even if you feel fine. Many people can keep their hypertension under control by making some changes in their daily activities, such as increasing exercise and eating a healthier diet. Other people may need to take medicine in addition to diet and/or exercise.
Hypertension Treatment
Hypertension, or high blood pressure, is dangerous because it can lead to strokes, heart attacks, heart failure, or kidney disease. The goal of hypertension treatment is to lower high blood pressure and protect important organs, like the brain, heart, and kidneys from damage. Treatment for hypertension has been associated with reductions in stroke (reduced an average of 35%-40%), heart attack (20%-25%), and heart failure (more than 50%), according to research.
Treating high blood pressure can help prevent serious — even life-threatening — complications. Your doctor also may suggest steps to control conditions that can contribute to high blood pressure, such as diabetes and high cholesterol.
The treatment for secondary pulmonary hypertension usually begins with treating the underlying cause. For instance, if a blood clot, or pulmonary embolism, is causing the hypertension, the clot may need to be surgically removed.
For individuals with hypertension, lifestyle modifications as mentioned above are important but many times, medications will also be needed to adequately manage blood pressure. Many types of drugs are used to lower blood pressure.

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Although Cancer is primarily a disease of the elderly with more than 60% of deaths from cancer occurring in those over the age of 65, cancer can strike even the youngest of children.

Cancer appears to occur when the growth of cells in the body is out of control and cells divide too rapidly. Cancer can develop in almost any organ or tissue, such as the lung, colon, breast, skin, bones, or nerve tissue.

Most common sites are:

• Prostrate 24%
• Breast 13%
• Lung 13%
• Colon and Rectum 9%
• Bladder 3%
• Uterus 2. 5%

The cause of Cancer is believed to be a combination of genetic factors and outside carcinogens such as tobacco, viruses, infection, asbestos, vinyl chloride, inappropriate diet.

Cancer often has no specific symptoms, so it is important that you limit your risk factors and undergo appropriate cancer screening. The signs and symptoms will depend on where the cancer is, the size of the cancer, and how much it affects the nearby organs or structures.

If a cancer spreads (metastasizes), then symptoms may appear in different parts of the body. As a cancer grows, it begins to push on nearby organs, blood vessels, and nerves. If the cancer is in a critical area, such as certain parts of the brain, even the smallest tumor can cause early symptoms.

But sometimes cancers start in places where it does not cause any symptoms until the cancer has grown quite large. Pancreatic cancers, for example, do not usually grow large enough to be felt from the outside of the body.

By the time a pancreatic cancer causes these signs or symptoms, it has usually reached an advanced stage.

A cancer may also cause symptoms common to many other problems, such as; fever, fatigue and weight loss. This may be because the cancer uses up much of the body s energy or it may cause the release of substances which affect metabolism.

Some lung cancers make hormone-like substances that affect blood calcium levels, affecting nerves and muscles and causing weakness and dizziness.

It is important to know what some of the general (non-specific) signs and symptoms of cancer are, but remember that having any of these does not mean that you have cancer.

Most cancers can be treated and some cured, depending on the specific type, location, and stage. The earlier the cancer is found, the better the prognosis.

A good example of the importance of finding cancer early is melanoma skin cancer. Skin cancer can be easy to remove if it has not grown deep into the skin, and the 5-year survival rate (percentage of people living at least 5 years after diagnosis) at this stage is nearly100%.

Screening for breast cancer with mammograms has been shown to reduce the average stage of diagnosis of breast cancer in a population.

Colorectal cancer can be detected through fecal occult blood testing and colonoscopy, which reduces both colon cancer incidence and mortality, presumably through the detection and removal of pre-malignant polyps.

Similarly, cervical cytology testing (using the Pap smear) leads to the identification and excision of precancerous lesions.

Testicular self-examination is recommended for men beginning at the age of 15 years to detect testicular cancer.

SIGNS and SYMPTOMS

Pain may be an early symptom with some cancers such as bone cancers or testicular cancer.

Long-term constipation, diarrhea, or a change in the size of the stool may be a sign of colon cancer.

Pain with urination, blood in the urine, or a change in bladder function (such as more frequent or less frequent urination) could be related to bladder or prostate cancer.

Skin cancers may bleed and look like sores that do not heal.

A long-lasting sore in the mouth could be an oral cancer and should be dealt with right away, especially in patients who smoke, chew tobacco, or frequently drink alcohol.

Sores on the penis or vagina may either be signs of infection or an early cancer, and should not be overlooked.

Unusual bleeding can happen in either early or advanced cancer.

Blood in the sputum (phlegm) may be a sign of lung cancer.

Blood in the stool (or a dark or black stool) could be a sign of colon or rectal cancer.

Blood in the urine may be a sign of bladder or kidney cancer.

A bloody discharge from the nipple may be a sign of breast cancer.

Many cancers can be felt through the skin, mostly in the breast, testicle, lymph nodes (glands), and the soft tissues of the body. A lump or thickening may be an early or late sign of cancer.

While they commonly have other causes, indigestion or swallowing problems may be a sign of cancer of the esophagus, stomach, or pharynx (throat).

A cough that does not go away may be a sign of lung cancer.

A cancer may be suspected for a variety of reasons, but the definitive diagnosis of most malignancies must be confirmed by histological examination of the cancerous cells by a pathologist.

TREATMENT

Once diagnosed, cancer is usually treated with a combination of surgery, chemotherapy and radiotherapy.

Radiation therapy may be used to treat almost every type of solid tumor, including cancers of the brain, breast, cervix, larynx, lung, pancreas, prostate, skin, stomach, uterus, or soft tissue sarcomas.

Most forms of chemotherapy target all rapidly dividing cells and are not specific for cancer cells, although some degree of specificity may come from the inability of many cancer cells to repair DNA damage, while normal cells generally can.

Contemporary methods for generating an immune response against tumours include intravesical BCG immunotherapy for superficial bladder cancer, and use of interferons and other cytokines to induce an immune response in renal cell carcinoma and melanoma patients.

Pain medication, such as morphine and oxycodone, and anti-emetics, drugs to suppress nausea and vomiting, are very commonly used in patients with cancer-related symptoms. transmission and disease.

Advances in cancer research have made a vaccine designed to prevent cancer available. The vaccine protects against four HPV types, which together cause 70% of cervical cancers and 90% of genital warts.

The consensus on diet and cancer is that obesity increases the risk of developing cancer. The cancer-fighting components of food are also proving to be more numerous and varied than previously understood, so patients are increasingly being advised to consume fresh, unprocessed fruits and vegetables for maximal health benefits.

Risk factors may be related to the environment, genetics and family history, smoking, diet, hormones, how much sodium (salt) you have in your diet or even the level of stress in your life.

Hypertension also increases your risk of having a stroke or heart attack, and can lead to other diseases as well as make other health conditions even worse. It is important to your health and your future to learn about the risk factors and by controlling and altering what you have control over you can change you decrease your risks.

• Exposure to environmental pollutants, such as tobacco smoke, vapors around the office, etc.
• Obesity – being over weight is a factor in hypertension, especially as one ages. Proper diet and weight loss may aid in reversing the associated problems.
• Lack of exercise – Daily ‘aerobic’ exercise (walking, swimming, running, cycling, etc. ) can be very beneficial in decreasing blood pressure, as well as helping with your weight .
• Stress – we could all benefit from a little less of this. Exercise also helps with reducing your stress.
• Lower Alcohol Consumption – Drinking excessively doubles your chances of suffering high blood pressure or a stroke.
• Medicines and prescriptions (Ritalin, hormones, steroids, anti-rejection medications), your doctor and pharmacist should be intimately aware of what you are taking. Illegal drugs can also cause you problems (amphetamines, cocaine, ecstasy).
• Diet – a diet high in sodium puts strain on the blood vessels by increasing the fluid volume in the body (salt attracts water)

These risks can be helped or even controlled with the help of a doctor

• Pregnancy – the extra volume of blood, plus toxemia from high dietary salt intake can put a great strain on the vascular system.
• Kidney failure – the body is unable to remove fluids from the body causing an increase in fluid volume and blood pressure.
• Right-sided Heart Failure – decreases the hearts ability to pump high volumes of fluid through the heart causing a back-up into the blood vessels

Risk Factors over which you have no control

• Family history of hypertension especially onset before the age of 50.
• Age -your increases your chances of getting hypertension
• Gender (male or female)
• Race (Afro-American)
• Nervous System disorders

Secondary Hypertension

While the single cause of Primary hypertension is not known, the cause(s) of Secondary hypertension is and it is usually caused by another condition or disease. Conditions such as arteriosclerosis, diabetes, kidney disease, or even from medications and pregnancy (Gestational hypertension and is one of the reasons your doctor wants to see you more frequently near the end).

Hypertension can be caused either by taking medications or by stopping medications too quickly. Medications such as corticosteroids, birth control pills and other hormones, migraine medications, and medications used for chronic anemia (erythropoieten). Also a number of over-the-counter medications such as cough/cold medications and medications for asthma can cause hypertension.

Medications for hypertension can also cause a rebound hypertension if they are not weaned off of slowly.

Street drugs that can cause hypertension include: alcohol, amphetamines, ecstasy (MDMA and derivatives), and cocaine.

A small number of people experience malignant hypertension. This is an extremely high blood pressure that causes swelling of the optic nerve (the nerve that control vision). This is considered a medical emergency. Many of your vital organs are in serious risk of injury including your brain, your eyes, blood vessels, heart, and kidneys.